Margot Robbie, Bobby Moynihan, Nathaniel Rateliff & the Night Sweats

S10 E01 • Monday, Sep 19, 2022 • Sep 19 • 45m

Jimmy takes a moment to break down all the Easter eggs and clues ahead of the release of Taylor Swift’s new album, Midnights, plays Blow Your Mind with guest Margot Robbie, catches up with Bobby Moynihan and welcomes musical guest Nathaniel Rateliff & the Night Sweats.

Kaley Cuoco, Mike Birbiglia, Ari Lennox

S10 E02 • Tuesday, Sep 20, 2022 • Sep 20 • 45m

Jimmy plays Virtual Reality Pictionary with guests Kaley Cuoco and Mike Birbiglia before welcoming musical guest Ari Lennox.

Eli Manning, Chef José Andrés, Ana Fabrega, Michael Rowland

S10 E03 • Wednesday, Sep 21, 2022 • Sep 21 • 45m

Jimmy plays Tonight at the Rock - Powered by Samsung Galaxy with Fortnite World Cup Champion Bugha before speaking with guests chef José Andrés and Ana Fabrega and welcoming stand-up comic Michael Rowland.

Tyler Perry, Stephen A. Smith, Blood Orange

S10 E04 • Thursday, Sep 22, 2022 • Sep 22 • 45m

Jimmy reads his favorite tweets with the hashtag #WorstFirstDate before speaking with guests Tyler Perry and Stephen A. Smith and welcoming musical guest Blood Orange.

Jon Hamm, Jurnee Smollett, The Smashing Pumpkins

S10 E05 • Friday, Sep 23, 2022 • Sep 23 • 45m

Jimmy plays Hey Robot with Jon Hamm, speaks with guest Jurnee Smollett and welcomes musical guest The Smashing Pumpkins.

Nick Kroll, Jenna Bush Hager, Raymond Lee, Colum Tyrrell

S10 E06 • Monday, Sep 26, 2022 • Sep 26 • 45m

Jimmy shares his favorite inspirational quotes to help everyone kick off their week with good vibes, then catches up with Nick Kroll, Jenna Bush Hager and Raymond Lee before welcoming stand-up comic Colum Tyrrell.

Kelly Ripa, Kid Cudi, Kid Cudi ft. Ty Dolla $ign

S10 E07 • Tuesday, Sep 27, 2022 • Sep 27 • 45m

Jimmy gets help from the audience to decide what he should post on Twitter in WeTweet, then catches up with Kelly Ripa and Kid Cudi before welcoming musical guest Kid Cudi featuring Ty Dolla $ign.

Miles Teller, Idina Menzel, Babyface ft. Baby Tate

S10 E08 • Wednesday, Sep 28, 2022 • Sep 28 • 45m

Jimmy runs through the results of some little-known polls in Tonight Show Polls, then catches up with Miles Teller and Idina Menzel before welcoming musical guest Babyface featuring Baby Tate.

Robert De Niro, Chloe Fineman, Arctic Monkeys

S10 E09 • Thursday, Sep 29, 2022 • Sep 29 • 45m

Jimmy reads his favorite tweets with the hashtag #IUsedToThink, then catches up with Robert De Niro and Chloe Fineman before welcoming musical guest Arctic Monkeys.

Zac Efron, Debbie Harry, Lea Michele

S10 E10 • Friday, Sep 30, 2022 • Sep 30 • 45m

Jimmy pens his weekly thank you notes, catches up with guests Zac Efron, Debbie Harry and Lea Michele and welcomes Michele for a musical performance.

Naomi Watts, Jacob Batalon, Justin Thomas, Sam Hunt

S10 E11 • Monday, Oct 3, 2022 • Oct 3 • 45m

Jimmy addresses Elon Musk unveiling the prototype for a humanoid robot, then catches up with Naomi Watts, Jacob Batalon and Justin Thomas before welcoming musical guest Sam Hunt.

Ralph Macchio, Jennifer Beals, Lea Thompson, Modern English

S10 E12 • Tuesday, Oct 4, 2022 • Oct 4 • 45m

Jimmy addresses Trump announcing a $475 million defamation lawsuit against CNN, then catches up with Ralph Macchio, Jennifer Beals and Lea Thompson before welcoming musical guest Modern English.

Reese Witherspoon, Kevin Nealon, Sabrina Wu

S10 E13 • Wednesday, Oct 5, 2022 • Oct 5 • 45m

Jimmy addresses Trump asking the Supreme Court to overturn a ruling that allows the Justice Department to review documents seized from Mar-a-Lago, then catches up with Reese Witherspoon and Kevin Nealon before welcoming stand-up comedian Sabrina Wu.

Jack Harlow, Dwyane Wade, Quavo & Takeoff

S10 E14 • Thursday, Oct 6, 2022 • Oct 6 • 45m

Jimmy and his co-host Jack Harlow compete in a basketball shooting contest using random objects, including a vase filled with applesauce, then catch up with Dwyane Wade before welcoming musical guests Quavo & Takeoff.

Mike Myers, Sutton Foster, Killer Mike

S10 E15 • Friday, Oct 7, 2022 • Oct 7 • 45m

Jimmy addresses Biden saying the world is at risk of a nuclear "Armageddon" amid rising tensions with Russia, then catches up with Mike Myers, Sutton Foster and Killer Mike before enjoying a musical performance from Killer Mike.

Rachel Maddow, Noah Centineo, Fabien Frankel, Remi Wolf

S10 E16 • Monday, Oct 10, 2022 • Oct 10 • 45m

Jimmy invites people all over the world to show off their talents for a brand-newShow Me Something Good and speaks with guests Rachel Maddow, Noah Centineo and Fabien Frankel before welcoming musical guest Remi Wolf.

Pierce Brosnan, Charlie Puth, Kate del Castillo

S10 E17 • Tuesday, Oct 11, 2022 • Oct 11 • 45m

Jimmy gets help from the audience to decide what he should post on Twitter in WeTweet, then catches up with Pierce Brosnan, musical guest Charlie Puth and Kate del Castillo.

Dwayne Johnson, Camila Cabello, Ian Lara

S10 E18 • Wednesday, Oct 12, 2022 • Oct 12 • 45m

Jimmy reads his favorite tweets with the hashtag #TextFail in an all-new Hashtags and catches up with guests Dwayne Johnson and Camila Cabello before welcoming comedian Ian Lara.

Trevor Noah, Antoni Porowski, Andrea Campos, Lil Baby

S10 E19 • Thursday, Oct 13, 2022 • Oct 13 • 45m

Jimmy writes his weekly Thank You Notes and speaks with guests Trevor Noah, Antoni Porowski and Andrea Campos before welcoming musical guest Lil Baby.

Taylor Swift, Meghan Trainor

S10 E20 • Monday, Oct 24, 2022 • Oct 24 • 45m

Jimmy takes a moment to highlight some Tonight Show sponsors, then catches up with Taylor Swift and Meghan Trainor before enjoying a musical performance from Trainor.

Sigourney Weaver, Michaela Coel, Zedd & Maren Morris

S10 E21 • Tuesday, Oct 25, 2022 • Oct 25 • 45m

Jimmy gets help from the audience to decide what he should post on Twitter in WeTweet, then catches up with Sigourney Weaver and Michaela Coel before enjoying a musical performance from Zedd and Maren Morris.

Jim Parsons, Rose Byrne, Isabel Hagen

S10 E22 • Wednesday, Oct 26, 2022 • Oct 26 • 45m

Jimmy reviews some interesting user data released by Spotify, then catches up with Jim Parsons and Rose Byrne before welcoming stand-up comedian Isabel Hagen.

Millie Bobby Brown, Michael Imperioli, Tegan and Sara

S10 E23 • Thursday, Oct 27, 2022 • Oct 27 • 45m

Jimmy reads his favorite tweets with the hashtag #LastMinuteCostumes, then catches up with Millie Bobby Brown and Michael Imperioli before welcoming musical guest Tegan and Sara.

Lin-Manuel Miranda; Bobby Cannavale; JVKE

S10 E24 • Friday, Oct 28, 2022 • Oct 28 • 45m

Daniel Radcliffe; Winston Duke; Caroline Rhea

S10 E25 • Monday, Oct 31, 2022 • Oct 31 • 45m

Lupita Nyong'o; "Weird Al" Yankovic; Cameron Crowe; A Performance from Almost Famous

S10 E26 • Tuesday, Nov 1, 2022 • Nov 1 • 45m

George Lopez; Cole Hauser; LaTanya Richardson Jackson; Joey Bada$$ with Men I Trust

S10 E27 • Wednesday, Nov 2, 2022 • Nov 2 • 45m

Hasan Minhaj; Bashir Salahuddin and Diallo Riddle; Paramore

S10 E28 • Thursday, Nov 3, 2022 • Nov 3 • 45m

Mariah Carey, Marcus Mumford ft. Monica Martin

S10 E29 • Friday, Nov 4, 2022 • Nov 4 • 45m

Ryan Reynolds; Jen Psaki; Smino

S10 E30 • Monday, Nov 7, 2022 • Nov 7 • 45m

Octavia Spencer; Matthias Schweighöfer; Kurt Braunohler

S10 E31 • Wednesday, Nov 9, 2022 • Nov 9 • 45m

Will Ferrell; Lindsay Lohan; The 1975

S10 E32 • Thursday, Nov 10, 2022 • Nov 10 • 45m

Sylvester Stallone; Linda Cardellini; Louis Tomlinson

S10 E33 • Friday, Nov 11, 2022 • Nov 11 • 45m

Bruce Springsteen; Chloe Grace Moretz

S10 E34 • Monday, Nov 14, 2022 • Nov 14 • 45m

Seth Rogen; Jeremy Pope; Bruce Springsteen

S10 E35 • Tuesday, Nov 15, 2022 • Nov 15 • 45m

Anya Taylor-Joy; Glen Powell; Patti Smith; Bruce Springsteen

S10 E36 • Wednesday, Nov 16, 2022 • Nov 16 • 45m

Jessica Chastain; Martha Steweart; The Smile

S10 E37 • Thursday, Nov 17, 2022 • Nov 17 • 45m

Samuel L. Jackson; Neal Brennan; Wizkid

S10 E38 • Friday, Nov 18, 2022 • Nov 18 • 45m

Tim Allen; Lacey Chabert; From "Bluey:, Dave McCormack & Melanie; Brent Faiyaz

S10 E39 • Monday, Nov 21, 2022 • Nov 21 • 45m

Michael Strahan; Chef Daniel Humm; Cole Swindell

S10 E40 • Tuesday, Nov 22, 2022 • Nov 22 • 45m

Jesse Eisenberg; Madelyn Cline; Jacques Pepin

S10 E41 • Wednesday, Nov 23, 2022 • Nov 23 • 45m

Jerry Seinfeld; Adam Devine; Bruce Springsteen

S10 E42 • Thursday, Nov 24, 2022 • Nov 24 • 45m

Zoe Saldana; James Austin Johnson; A Performance from & Juliet

S10 E43 • Monday, Nov 28, 2022 • Nov 28 • 45m

Whoopi Goldberg; Sam Worthington; Gabe LaBelle; Manuel Turizo

S10 E44 • Tuesday, Nov 29, 2022 • Nov 29 • 45m

Dolly Parton; Claire Foy; DOMi & JD BECK; Mac DeMarco

S10 E45 • Wednesday, Nov 30, 2022 • Nov 30 • 45m

Adam Sandler; Greta Gerwig; Dane Cook; Babyface Ray; Keke Palmer

S10 E46 • Thursday, Dec 1, 2022 • Dec 1 • 45m

Kevin Bacon; Theo James; Jay Jurden

S10 E47 • Friday, Dec 2, 2022 • Dec 2 • 45m

Selena Gomez; Sebastian Maniscalco; beabadoobee

S10 E48 • Monday, Dec 5, 2022 • Dec 5 • 45m

Emma Thompson; Guillermo del Toro; Ashley McBryde; John Osborne

S10 E49 • Tuesday, Dec 6, 2022 • Dec 6 • 45m

Michelle Pfeiffer; Lil Rel Howery; Clive Davis; Goose

S10 E50 • Wednesday, Dec 7, 2022 • Dec 7 • 45m