Michael Keaton

as Samuel Finnix

8 episodes

Peter Sarsgaard

as Rick Mountcastle

8 episodes

Michael Stuhlbarg

as Richard Sackler

8 episodes

Will Poulter

as Billy Cutler

8 episodes

John Hoogenakker

as Randy Ramseyer

8 episodes

Kaitlyn Dever

as Betsy Mallum

8 episodes

Rosario Dawson

as Bridget Meyer

8 episodes

Will Chase

as Michael Friedman

8 episodes

Cleopatra Coleman

as Grace Pell

8 episodes

Mare Winningham

as Diane Mallum

7 episodes

Ian Unterman

as Jonathan Sackler

7 episodes

Jake McDorman

as John Brownlee

7 episodes

Phillipa Soo

as Amber Collins

7 episodes

Brendan Patrick Connor

as Howard Udell

7 episodes

Andrea Frankle

as Beth Sackler

7 episodes

Arischa Conner

as Leah Turner

6 episodes

Winsome Brown

as Theresa Sackler

6 episodes

Andrés Erickson

as Mortimer D.A. Sackler

6 episodes

Jaime Ray Newman

as Kathe Sackler

5 episodes

Lawrence Arancio

as Raymond Sackler

5 episodes

Raúl Esparza

as Paul Mendelson

5 episodes

Ray McKinnon

as Jerry Mallum

5 episodes

Deadra Moore

as Karen Johnson

5 episodes

Alayna Hester

as Elizabeth Ann McClung

5 episodes

Rick Espaillat

as Dr. Alan Spanos

4 episodes